Tatsuhiro Akaishi Selected Research

CNB 001

1/2020	The Synthetic Curcumin Derivative CNB-001 Attenuates Thrombin-Stimulated Microglial Inflammation by Inhibiting the ERK and p38 MAPK Pathways.
1/2018	CNB-001, a synthetic pyrazole derivative of curcumin, suppresses lipopolysaccharide-induced nitric oxide production through the inhibition of NF-κB and p38 MAPK pathways in microglia.

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Tatsuhiro Akaishi Research Topics

Disease

5	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 10/2008
2	Inflammation (Inflammations) 01/2020 - 01/2012
1	Wounds and Injuries (Trauma) 01/2020
1	Amyloid Plaque 01/2014
1	Cognitive Dysfunction 01/2011
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2011
1	Memory Disorders (Memory Loss) 10/2006

Drug/Important Bio-Agent (IBA)

3	Pharmaceutical PreparationsIBA 03/2012 - 10/2008
2	CurcuminIBA 01/2020 - 01/2018
2	CNB 001IBA 01/2020 - 01/2018
2	Proteins (Proteins, Gene)FDA Link 01/2014 - 01/2011
2	Amyloid beta-PeptidesIBA 01/2011 - 10/2008
2	Biological ProductsIBA 10/2008 - 10/2006
2	fisetinIBA 10/2008 - 10/2006
1	p38 Mitogen-Activated Protein KinasesIBA 01/2020
1	2-f)quinazoline-1,3-diamine N3- cyclopropyl- 7- ((4- (1- methylethyl)phenyl)methyl)- 7H- pyrrolo(3IBA 01/2020
1	Serine Proteases (Serine Protease)IBA 01/2020
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2020
1	PAR-1 ReceptorIBA 01/2020
1	Thrombin FDA Link 01/2020
1	pyrazoleIBA 01/2018
1	Amyloid (Amyloid Fibrils)IBA 01/2014
1	ProstaglandinsIBA 01/2012
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2012
1	LigandsIBA 01/2011